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Image Search Results
Journal: bioRxiv
Article Title: An integrative approach for profiling antibody responses in bats to human pathogens
doi: 10.1101/2024.11.29.626104
Figure Lengend Snippet: High throughput analyses of reactivity of bat antibodies. a . Plots depicting the mean fluorescence intensity of the raw signal from microarray chips. Each spot indicates the binding intensity of bat antibodies to a single peptide. b . Heat-map of MFI values obtained after subtraction of the background. Each line in the graph represents the reactivity to a single peptide in the array. Statistical analyses were performed by a Wilcoxon two-tailed test to compare the mean antibody binding reactivity for the indicated conditions. c . Plots depicting the values of Z scores. The dashed gray lines correspond to Z score of 2, which is considered as a threshold of significance. Each dot in the plots corresponds to the Z score of antibody reactivity to a single peptide. d . Heat map and hierarchical clustering of Z scores depicting the reactivity of bat antibodies to peptides in microarrays. Each column in the heat maps displays the binding intensity of a single peptide. The average of each column in the map is always equal to 0. The map distinguished six clusters of peptides.
Article Snippet: The
Techniques: High Throughput Screening Assay, Fluorescence, Microarray, Binding Assay, Two Tailed Test